Write an account of lead discovery and optimization consulting

Assists in proposal writing and presentations, including online and video. Monitors profitability and performance of existing products and services.

Eisenhardt 's methodological work.

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Yin 's guidelines and making positivist assumptions. There are substantial methodological differences between these approaches. Case selection and structure[ edit ] An average, or typical case, is often not the richest in information.

In clarifying lines of history and causation it is more useful to select subjects that offer an interesting, unusual or particularly revealing set of circumstances. A case selection that is based on representativeness will seldom be able to produce these kinds of insights. When selecting a case for a case study, researchers will therefore use information-oriented sampling, as opposed to random sampling.

Alternatively it may be chosen because of researchers' in-depth local knowledge; where researchers have this local knowledge they are in a position to "soak and poke" as Richard Fenno put it, [15] and thereby to offer reasoned lines of explanation based on this rich knowledge of setting and circumstances.

Three types of cases may thus be distinguished for selection: Key cases Outlier cases Local knowledge cases Whatever the frame of reference for the choice of the subject of the case study key, outlier, local knowledgethere is a distinction to be made between the subject and the object of the case study.

The subject is the "practical, historical unity" through which the theoretical focus of the study is being viewed.

Thus, for example, if a researcher were interested in US resistance to communist expansion as a theoretical focus, then the Korean War might be taken to be the subject, the lens, the case study through which the theoretical focus, the object, could be viewed and explicated.

Gary Thomas thus proposes a typology for the case study wherein purposes are first identified evaluative or exploratorythen approaches are delineated theory-testing, theory-building or illustrativethen processes are decided upon, with a principal choice being between whether the study is to be single or multiple, and choices also about whether the study is to be retrospective, snapshot or diachronic, and whether it is nested, parallel or sequential.

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The typology thus offers many permutations for case-study structure. These are, to a differentiable degree, similar to the case study in that many contain reviews of the relevant literature of the topic discussed in the thorough examination of an array of cases published to fit the criterion of the report being presented.

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These case reports can be thought of as brief case studies with a principal discussion of the new, presented case at hand that presents a novel interest. In a case where the market of any organisation is in a messy state, the agency will always seek to find out some of the reasons why the scenario is that way.

write an account of lead discovery and optimization consulting

They will have to gather information that may help them in solving such issues. For this to be fully achieved, one must be able to carry out a market research to establish where the problem is. This, therefore, calls for the different methods which can be used in a situation where one wants to conduct a marketing research.

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The organisations have to choose one of the available techniques so that they can thoroughly conduct their investigations. Some of the primary methods that would be used included interviews, surveys, focus groups, observations and in some cases use field trials.

Types of case studies[ edit ] In public-relations research, three types of case studies are used: Under the more generalized category of case study exist several subdivisions, each of which is custom selected for use depending upon the goals of the investigator.

These types of case study include the following:Jun 26,  · Lead optimization using drug metabolism and pharmacokinetics (DMPK) parameters has become one of the primary focuses of research organizations involved in drug discovery in the last decade.

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Using a combination of rapid in vivo and in vitro DMPK screening procedures on a large array of compounds. Browse Current Job Openings Below. We believe that candidates are also our customers and we treat you as such.

write an account of lead discovery and optimization consulting

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Lead Discovery Approaches to Searching for Hits • Traditional Library Screening called leads and advanced for further optimization of activity, selectivity, and biologi-cal behavior.

Occasionally, leads are found through other methods, such as serendipity promising hits for the lead optimization stage.

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